A window into the body: groundbreaking technique makes skin transparent

transparent skin on wrist

Using common food dye, researchers make skin, muscle safely and reversibly transparent


September 9, 2024

Researchers have developed a new way to see organs within a body by rendering overlying tissues transparent to visible light.

The counterintuitive process—a topical application of food-safe dye—was reversible in tests with animal subjects, and may ultimately apply to a wide range of medical diagnostics, from locating injuries to monitoring digestive disorders to identifying cancers. 

″Looking forward, this technology could make veins more visible for the drawing of blood, make laser-based tattoo removal more straightforward, or assist in the early detection and treatment of cancers,″ said Stanford University assistant professor of materials science and engineering Guosong Hong, a U.S. National Science Foundation CAREER grantee who helped lead this work. ″For example, certain therapies use lasers to eliminate cancerous and precancerous cells, but are limited to areas near the skin’s surface. This technique may be able to improve that light penetration.″

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The U.S. National Science Foundation propels the nation forward by advancing fundamental research in all fields of science and engineering. NSF supports research and people by providing facilities, instruments and funding to support their ingenuity and sustain the U.S. as a global leader in research and innovation. With a fiscal year 2023 budget of $9.5 billion, NSF funds reach all 50 states through grants to nearly 2,000 colleges, universities and institutions. Each year, NSF receives more than 40,000 competitive proposals and makes about 11,000 new awards. Those awards include support for cooperative research with industry, Arctic and Antarctic research and operations, and U.S. participation in international scientific efforts.

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